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Showing posts from August, 2018

Food Toxicology

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The Toxicology is the branch of science that deals with the adverse effects of chemicals on living organisms and leads to fatal condition in living organism. Toxicology is interface of chemistry and biology.   – Pharmacology: therapeutic effect   – Toxicology: toxicosis or disease effect Food toxicology deals with physical, chemical and biological properties of food particles and detection of toxic substances in food, and their diseases and infections. Some food items are poisonous and some are medicinal , stimulatory, hallucinatory, or narcotic effects. Toxicology in two categories: basic and Fundamental. Fundamental work on the molecular and biological processes of toxic substances is called Basic toxicology. Applying scientific knowledge to practical problems is called Applied Toxicology. Toxicology vs. Risk analysis: In majority of Risk analysis only the applied toxicology is used to examine whether there is the presence of chemical, natural and anthropogeni

Drug Discovery and Development

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At initial stage of Drug   Discovery , based on the single molecule disease target, scientist identifies the high specificity compound which modulates and interacts with the target. The approach used by them was “ one target and one drug” approach which is the failure one. Thus, result in the intake of series of specific target drugs which reacts in ineffective way to the isolated target. The new drugs are prepared well than the previous generation to increase the life, strength, reduces the pain and suffering. The development of new drugs makes the pharma industry to take risk in cost and time. The new Drugs are discovered in the basis of cheap (to the people) and more effective. The various phase are there for drug discovery and development, at last the drug enters via New Drug Application (NDA) and then launched into the market only by satisfying FDA rules and regulations. The base for the drugs is synthetic molecules, which is directly, or indirectly a natural product or polycon